Satoshi Kuwabara (The Quintessential Quintuplets) is directing the anime at Tezuka Productions. Keiichirō Ōchi (The Quintessential Quintuplets) is in charge of series scripts. Akiko Toyoda (Yu-Gi-Oh!: The Dark Side of Dimensions) is designing the characters and serving as chief animation director. Keiichirō Ōchi, Kazuhiko Inukai, and Mayumi Morita are writing the scripts. Miki Sakurai and Tatsuhiko Saiki are composing the music

The new isekai fantasy series centers on the protagonist Reiji Kirio, who is reincarnated into another world and uses his "Medicine Maker" skill to create innovative medicines one after another and opens a drugstore. The anime directed by Masafumi Sato (Denkigai no Honya-san) is set to premiere in Japan on July 7, 2021. And a character PV for Ejiru will be posted on June 30, then that of Mina will follow on July 7.
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Just some notes that the above totals may not include some online retailers, like the ufotable WEBSHOP, which saw the site break under the heavy load of people trying to get pre-orders and have since said that any orders going of Mugen Train will be shipped one to three weeks after purchase.
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Tanabe published the original story in the 1985 short story collection of the same name. The story inspired a live-action film in 2003.
Also, the DVD and Blu-ray of their final concert "i☆Ris LIVE 2021 ~storiez~" and the music video collection Blu-ray "i☆Ris Music Video Collection 2012-2020" are set to be released simultaneously on July 7, 2021, the ninth anniversary day of their formation.
This is the band's second anime theme song work following the OP theme for the TV anime Eagle Talon: Golden Spell in 2020. The band's guitarist Asahi says, "In Aho-Girl, the protagonist was aho (an idiot), but this time, everyone is aho, so it's very fun. We tried our best to make this comedy as hilarious as possible."
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